cagA protein (80R-4275)
Purified Recombinant cagA protein (N terminal His-Sumo tag)
Overview
Overview
| Synonyms | Helicobacter pylori virulence factor CagA protein, H pylori virulence factor CagA protein, Cytotoxin-associated gene A protein, Recombinant Helicobacter pylori Cytotoxicity-associated immunodominant antigen, cai protein |
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| Species | Viral |
| Protein Type | Recombinant |
Specifications
| Residues | C terminal amino acids 918-1147 with N-terminal his-sumo tag. |
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| Expression System | E.coli |
| Grade & Purity | > 90% pure |
| Tag/Conjugate | His-Sumo tag |
| Form & Buffer | Supplied in a Tris-based buffer with 50% glycerol |
Storage & Safety
| Storage | Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week |
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General Information
| Biological Significance | cagA protein is a 120–145kDa protein encoded on the 40kb cag pathogenicity island (PAI). H. pylori strains can be divided into CagA positive or negative strains. Around 60% of H. pylori isolates in Western countries are positive, whereas the majority of East Asian isolates are positive. |
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