Calcitonin antibody (10-2268)

Recombinant Fab monoclonal Calcitonin antibody

Synonyms Monoclonal Calcitonin antibody, Anti-Calcitonin antibody, CALCA antibody, CALC1 antibody, CGRP antibody, CGRP-I antibody, CGRP1 antibody, CT antibody, KC antibody, Calcitonin 1 antibody, thyrocalcitonin antibody
Specificity Human
Cross Reactivity Detects Procalcitonin but its sandwich pair partner, 10-2269 does not.
Protein Type Recombinant
Applications ELISA
Assay Information Calcitonin antibody pair: 10-2269 can be used as the capture antibody with 10-2268 as the detection antibody for detection of human Calcitonin in ELISA

Specifications

Host Mouse
Clone M72051
Isotype IgG1 kappa - Fab fragment
Expression System E.coli
Grade & Purity > 95% pure
Method of Purification Calcitonin antibodies screened using Phage Display system. Expressed in and purified from E. coli.
Tag/Conjugate His tag
Form & Buffer Supplied as liquid in 50 mM Potassium Phosphate, 10 mM Boric Acid, 150 mM NaCl, pH 7
Concentration > 1 mg/ml

Storage & Safety

Storage Store at -20 deg C in small aliquots. Avoid repeated freeze thawing.

General Information

Biological Significance Calcitonin is a 32-amino acid linear polypeptide hormone that is produced in humans primarily by the parafollicular cells (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchial body. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). Calcitonin antibody was produced as a recombinant Fab monoclonal antibody in a Phage Display system. This anti-Calcitonin antibody is used for detection of human Calcitonin in ELISA. The concentration of the antibody ranges from 1 mg/ml to 25 mg/ml depending on the lot. Recombinant Fab monoclonal antibodies have a number of advantages over standard antibodies including; improved scale up for batch consistency, more efficient binding so less antibody required, more accurate binding meaning fewer conjugation issues, less non specific due to removal of the Fc region, more flexibility for purification and labeling through a C-terminal His tag.

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Availability: In stock

Price From: Price: €274.85
Price From: Price: €274.85
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