Calcitonin antibody (10-2366)
Mouse Monoclonal Calcitonin antibody
Overview
Overview
| Synonyms | Monoclonal Calcitonin antibody, Anti-Calcitonin antibody, CGRP antibody, CGRP-I antibody, CGRP1 antibody, CT antibody, KC antibody, Thyrocalcitonin antibody, CALCA antibody, CALC1 antibody |
|---|---|
| Specificity | Recognizes natural Human CT |
| Applications | ELISA, Lateral Flow, RIA |
| Immunogen | Calcitonin antibody was raised in Mouse using Human synthetic CT as the immunogen |
| Assay Information | 10-2366 can be used as the detection antibody in a matched pair immunoassay in conjunction with 61-1050, 10-2367 or 10-2368 as the capture antibody |
Specifications
| Host | Mouse |
|---|---|
| Clone | M83095 |
| Isotype | IgG1 kappa |
| Method of Purification | Calcitonin antibody was purified by urified by Protein A affinity chromatography |
| Form & Buffer | Supplied in liquid form in 0.1 M PBS buffer, pH 7.4 with 4% Saccharose |
| Concentration | 1-2 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage or aliquot and store at-20 deg C for longer terms. Avoid repeat freeze/thaw cycles |
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General Information
| Biological Significance | Calcitonin is a protein containing 32 amino acids that is synthesized by and secreted from parafollicular cells. Parafollicular cells lie between the thyroid follicular cells, and, during embryonic development, these cells migrate into the substance of the thyroid gland from a fetal structure called a branchial pouch. Calcitonin acts to decrease serum calcium concentrations by inhibiting the activity of the osteoclasts in bone tissue and by increasing calcium excretion in the urine. |
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