Calretinin protein (30R-2717)
Purified recombinant Mouse Calretinin protein
Overview
Overview
| Synonyms | Calretinin protein, calbindin 2 protein, CR protein, Calb2 protein |
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| Species | Mouse |
| Protein Type | Recombinant |
Specifications
| Expression System | E.coli |
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| Grade & Purity | > 90% pure |
| Method of Purification | Calretinin protein was purified using a a proprietary chromatographic technique. |
| Molecular Weight | 57 kDa |
| Form & Buffer | Supplied as a sterile filtered liquid in 50 mM Tris-Acetate, pH 7.5, 1 mM EDTA, 20% glycerol |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | <0.1 ng/ug |
General Information
| Biological Significance | Calretinin is an intracellular calcium-binding protein belonging to the troponin C superfamily characterized by a structural motif described as the EF-hand domain. The immunohistochemical detection of calretinin in developing cerebellum is restricted to the later stages indicated by weak staining from week 21 of gestation, in Purkinje and basket cells and in neurons of the dentate nucleus. The intensity of staining increases as the cerebellum matures. In tumors, calretinin has been detected in mesotheliomas and some pulmonary adenocarcinomas. |
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