Canine Adenovirus Type 1 protein (30-1933)
Native Canine Adenovirus Type 1 antigen
Overview
Overview
| Synonyms | Canine Adenovirus 1 protein, Canine Adenovirus Type 1 antigen, Canine Adenovirus protein, Canine Adenovirus antigen, Dog Adenovirus 1 protein, Dog Adenovirus Type 1 antigen, Dog Adenovirus protein, Dog Adenovirus antigen, Canine Hepatitis protein, CAV1 protein, CAV-1 protein |
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| Protein Type | Native |
Specifications
| Source | Produced in A72 cells |
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| Form & Buffer | Supplied in 50 mM Glycine buffer, pH 9.0 with 140 mM NaCl and <0.1% CHAPS |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store in aliquots at -70 deg C. Avoid repeated freeze thaw cycles. |
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| Biohazard Information | This material has been detergent and UV inactivated. However, it should be handled as potentially infectious. |
General Information
| Biological Significance | Adenoviruses (members of the family Adenoviridae) are medium-sized (90–100 nm), non enveloped viruses with an icosahedral nucleocapsid containing a double stranded DNA genome. Their name derives from their initial isolation from human adenoids in 1953. Two types of canine adenoviruses are well known, type 1 and 2. Type 1 causes infectious canine hepatitis, a potentially fatal disease involving vasculitis and hepatitis. |
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| Implications in Disease | Canine Adenovirus 1 (CAV-1) causes hepatitis in dogs resulting in upper respiratory tract infections. This virus targets the parenchymal (functional) parts of the organs, notably the liver, kidneys, eyes and endothelial cells (the cells that line the interior surface of the blood vessels). |
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