Canine NT-proBNP protein (30-1948)
Recombinant Canine NT-proBNP protein
Overview
Overview
| Synonyms | Recombinant Canine NT-proBNP protein, proBNP protein, Canine NT-proBNP antigen, pro Brain Natriuretic Peptide antigen, N-terminal proBNP protein, Canine pro Brain Natriuretic Peptide protein |
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| Protein Type | Recombinant |
| Applications | Control |
Specifications
| Residues | Amino acids 1-85 with proprietary affinity tag of 16 amino acids on the N-terminus. |
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| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Method of Purification | Purified using affinity tag chromatography |
| Molecular Weight | 10.5 kDa |
| Form & Buffer | Supplied as liquid in 10 mM potassium phosphate pH 7.4, 150 mM NaCl. |
Storage & Safety
| Storage | Store at -70 deg C in small aliqouts. |
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General Information
| Product Use | For use as a standard in proBNP detection assays |
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| Biological Significance | Brain natriuretic peptide or B-type natriuretic peptide (BNP) (also ventricular natriuretic peptide or natriuretic peptide B) is a 32-amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). |
| Implications in Disease | Circulating concentrations of proBNP and its N-terminal pro-hormone are raised in both symptomatic and asymptomatic patients with left ventricular dysfunction. |
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