Canstatin antibody (70R-14060)

Affinity purified Rabbit polyclonal Canstatin antibody

Synonyms Polyclonal Canstatin antibody, Anti-Canstatin antibody
Applications ICC, IHC-F, IHC-P, WB
Immunogen Canstatin antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human Canstatin, identical to the related rat and Rabbit sequences, as the immunogen

Images

Immunohistochemical staining using Canstatin antibody (70R-14060)

Immunohistochemistry of frozen section of Rat Kidney Tissue Lysate

Specifications

Host Rabbit
Isotype IgG
Method of Purification Canstatin antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using Canstatin antibody (70R-14060)</font></div>     | Immunohistochemistry of frozen section of Rat Kidney Tissue Lysate
  • <div><font face=Calibri size=2>Western Blot analysis using Canstatin antibody (70R-14060)</font></div>     | Lane 1: Rat Kidney Tissue Lysate

Availability: In stock

Price: €377.10
Size: 100 ug
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