Cardiac Troponin 1 Calibrator Set (35R-AT01)

Human Cardiac Troponin 1 Calibrator/Standard Set

Synonyms Troponin I Calibrator Set
Species Human
Protein Type Native
Applications User optimized

Specifications

Source Human cardiac muscle
Form & Buffer Lyophilized from solutions of native human troponin complex in normal human serum. Reconstitute with laboratory grade water.

Storage & Safety

Storage Store at -70 deg C in lyophilised and reconstituted forms. Aliquot following reconstitution and avoid repeated freeze/thaw cycles.
Biohazard Information Donor samples were tested and found negative for HBsAg, HCV and HIV 1 + 2 antibodies. Calibrators contain human blood components. As all blood derivatives should be considered as potentially infectious, it is recommended that these reagents be handled usi

General Information

Biological Significance Human troponin I is presented in cardiac muscle tissue by a single isoform with molecular weight 23876 Da and it consists of 209 amino acid residues. cTnI molecule contains two serines in the 22 and 23 positions. Both amino acid residues can be phosphorylated in vivo by protein kinase A, so four forms of protein ? one dephospho, two monophospho and one bisphospho ? can coexist in the cell.

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