CASP7 antibody (70R-13981)
Affinity purified Rabbit polyclonal CASP7 antibody
Overview
Overview
| Synonyms | Polyclonal CASP7 antibody, Anti-CASP7 antibody, caspase 7, CASP7, apoptosis-related cysteine peptidase antibody, CASP 7, CASP-7 antibody, CMH-1 antibody, MCH3 antibody, CASP-7, ICE-LAP3 antibody, CASP 7 antibody |
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| Applications | IHC-P, WB |
| Immunogen | CASP7 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of human CASP7 (p11), different from the related Rabbit and rat sequence by two amino acids, as the immunogen |
Images
Western Blot analysis using CASP7 antibody (70R-13981)
Lane 1: Hela Cell Lysate; Lane 2: MCF-7 Cell Lysate; Lane 3: SMMC Cell Lysate
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | CASP7 antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in lyophilized form |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by the end user |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. |
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