Caspase 1 antibody (70R-13979)

Affinity purified Rabbit polyclonal Caspase 1 antibody

Synonyms Polyclonal Caspase 1 antibody, Anti-Caspase 1 antibody, Caspase-1 antibody, Caspase -1, Caspase -1 antibody, Caspase 1, Caspase 1 antibody, Caspase 1, Cysteine-Aspartic Acid Protease antibody
Applications IHC-P, WB
Immunogen Caspase 1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human Caspase 1(p20) as the immunogen

Images

Immunohistochemical staining using Caspase 1 antibody (70R-13979)

Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification Caspase 1 antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 1 (ICE, interleukin 1 converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin 1 and IL 18 into active cytokines. Like other caspases, Caspase 1 itself is synthesized as a pro enzyme that is cleaved during activation into a large (20 kDa) and small (10 kDa) subunits. The cellular role of Caspase 1 appears limited to cytokine activation as they do not have obvious roles in apoptosis.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using Caspase 1 antibody (70R-13979)</font></div>     | Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue
  • <div><font face=Calibri size=2>Western Blot analysis using Caspase 1 antibody (70R-13979)</font></div>     | Lane 1: Jurkat Cell Lysate; Lane 2: Raji Cell Lysate; Lane 3: CEM Cell Lysate; Lane 4: PC-12 Cell Lysate

Availability: In stock

Price: €220.86
Size: 100 ug
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