Caspase 8 antibody (70R-13850)

Affinity purified Rabbit polyclonal Caspase 8 antibody

Synonyms Polyclonal Caspase 8 antibody, Anti-Caspase 8 antibody, Caspase -8 antibody, Caspase-8 antibody, Cysteine-Aspartic Acid Protease 8 antibody, Caspase 8 antibody, Caspase 8, Caspase 8, Caspase -8
Applications WB
Immunogen Caspase 8 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of human Caspase-8(P18), different to the related Rabbit sequence by a single amino acid, as the immunogen

Images

Western Blot analysis using Caspase 8 antibody (70R-13850)

Lane 1: Rat Thymus Tissue Lysate; Lane 2: Rat Liver Tissue Lysate; Lane 3: MCF-7 Cell Lysate; Lane 4: Hela Cell Lysate; Lane 5: SMMC Cell Lysate; Lane 6: Jurkat Cell Lysate; Lane 7: Colo320 Cell Lysate

Specifications

Host Rabbit
Isotype IgG
Method of Purification Caspase 8 antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 8 is a 55 kDa cytosolic protein that is synthesized as an inactive pro enzyme. Activation of Caspase 8 involves a two step proteolysis: the cleavage of Caspase 8 to generate a 43 and a 12 kDa fragment which is further processed to 10 kDa. The p43 is then cleaved to yield p26 and the release of the active site containing p18.

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Images

  • <div><font face=Calibri size=2>Western Blot analysis using Caspase 8 antibody (70R-13850)</font></div>     | Lane 1: Rat Thymus Tissue Lysate; Lane 2: Rat Liver Tissue Lysate; Lane 3: MCF-7 Cell Lysate; Lane 4: Hela Cell Lysate; Lane 5: SMMC Cell Lysate; Lane 6: Jurkat Cell Lysate; Lane 7: Colo320 Cell Lysate

Availability: In stock

Price: €220.86
Size: 100 ug
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