BBS4 antibody (70R-4575)
Rabbit polyclonal BBS4 antibody raised against the N terminal of BBS4
Overview
Overview
| Synonyms | Polyclonal BBS4 antibody, Anti-BBS4 antibody, Bardet-Biedl Syndrome 4 antibody |
|---|---|
| Specificity | BBS4 antibody was raised against the N terminal of BBS4 |
| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | BBS4 antibody was raised using the N terminal of BBS4 corresponding to a region with amino acids YVQALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAA |
| Assay Information | BBS4 Blocking Peptide, catalog no. 33R-10282, is also available for use as a blocking control in assays to test for specificity of this BBS4 antibody |
Images
Western Blot analysis using BBS4 antibody (70R-4575)
BBS4 antibody (70R-4575) used at 1 ug/ml to detect target protein.
Specifications
| Host | Rabbit |
|---|---|
| Method of Purification | Affinity purified |
| Molecular Weight | 58 kDa (MW of target protein) |
| Form & Buffer | Supplied as liquid, in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 1 ug/ml |
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Storage & Safety
| Storage | Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles. |
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General Information
| Biological Significance | This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. |
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