SMPD3 antibody (70R-7194)
Rabbit polyclonal SMPD3 antibody
Overview
Overview
| Synonyms | Polyclonal SMPD3 antibody, Anti-SMPD3 antibody, SMPD-3, SMPD 3, Neutral Sphingomyelinase Ii antibody, MGC138443 antibody, Sphingomyelin Phosphodiesterase 3 Neutral Membrane antibody, SMPD 3 antibody, SMPD3, NSMASE2 antibody, FLJ22593 antibody, SMPD-3 antibody |
|---|---|
| Cross Reactivity | Human,Mouse,Rat |
| Applications | WB |
| Immunogen | SMPD3 antibody was raised using a synthetic peptide corresponding to a region with amino acids RPPEADDPVPGGQARNGAGGGPRGQTPNHNQQDGDSGSLGSPSASRESLV |
| Assay Information | SMPD3 Blocking Peptide, catalog no. 33R-8099, is also available for use as a blocking control in assays to test for specificity of this SMPD3 antibody |
Images
Western Blot analysis using SMPD3 antibody (70R-7194)
SMPD3 antibody (70R-7194) used at 1 ug/ml to detect target protein.
Specifications
| Host | Rabbit |
|---|---|
| Method of Purification | Affinity purified |
| Molecular Weight | 71 kDa (MW of target protein) |
| Form & Buffer | Supplied as liquid, in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 1 ug/ml |
|---|
Storage & Safety
| Storage | Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles. |
|---|
General Information
| Biological Significance | SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. SMPD3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It probably acts as a regulator of postnatal development and participates in bone and dentin mineralization. |
|---|
Reviews
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product