FBXL11 antibody was raised in rabbit using the N terminal of FBXL11 as the immunogen
Assay Information
FBXL11 Blocking Peptide, catalog no. 33R-7980, is also available for use as a blocking control in assays to test for specificity of this FBXL11 antibody
Immunohistochemical staining using FBXL11 antibody (70R-7879)
FBXL11 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Skeletal muscle cells (arrows) in Human Muscle. Magnification is at 400X
FBXL11 antibody
Immunohistochemical staining using FBXL11 antibody (70R-7879)
FBXL11 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Skeletal muscle cells (arrows) in Human Muscle. Magnification is at 400X
Western Blot analysis using FBXL11 antibody (70R-7879)
FBXL11 antibody (70R-7879) used at 0.2-1 ug/ml to detect target protein.
Specifications
Host
Rabbit
Form & Buffer
Supplied as liquid, in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.
General Information
Biological Significance
FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box). The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL11 belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats