TUSC4 antibody (70R-8928)
Affinity purified rabbit polyclonal TUSC4 antibody
Overview
Overview
| Synonyms | Polyclonal TUSC4 antibody, Anti-TUSC4 antibody, TUSC 4 antibody, TUSC4, NPRL2 antibody, NPR2L antibody, TUSC-4 antibody, TUSC 4, TUSC-4, tumor suppressor candidate 4 antibody |
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| Cross Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Immunogen | TUSC4 antibody was raised in rabbit using the middle region of TUSC4 as the immunogen |
| Assay Information | TUSC4 Blocking Peptide, catalog no. 33R-8625, is also available for use as a blocking control in assays to test for specificity of this TUSC4 antibody |
Images
Western Blot analysis using TUSC4 antibody (70R-8928)
Western Blot showing TUSC4 antibody used at a concentration of 1-2 ug/ml to detect its target protein.
Specifications
| Host | Rabbit |
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| Form & Buffer | Supplied as liquid, in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 0.2-1 ug/ml |
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Storage & Safety
| Storage | Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | TUSC4 suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. TUSC4 down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. TUSC4 may act as a tumor suppressor. TUSC4 suppresses cell growth and enhanced sensitivity to various anticancer drugs. |
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