CASP8AP2 antibody (70R-8932)
Affinity purified rabbit polyclonal CASP8AP2 antibody
Overview
Overview
| Synonyms | Polyclonal CASP8AP2 antibody, Anti-CASP8AP2 antibody, CASPAP2 8 antibody, FLASH antibody, RIP25 antibody, KIAA1315 antibody, CASPAP2-8, CASP8 associated protein 2 antibody, FLJ11208 antibody, CASP8AP2, CASPAP2-8 antibody, CASPAP2 8, CED-4 antibody |
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| Cross Reactivity | Human, Mouse, Rat, Bovine, Dog |
| Applications | WB |
| Immunogen | CASP8AP2 antibody was raised in rabbit using the N terminal of CASP8AP2 as the immunogen |
| Assay Information | CASP8AP2 Blocking Peptide, catalog no. 33R-8602, is also available for use as a blocking control in assays to test for specificity of this CASP8AP2 antibody |
Images
Western Blot analysis using CASP8AP2 antibody (70R-8932)
CASP8AP2 antibody (70R-8932) used at 0.2-1 ug/ml to detect target protein.
Specifications
| Host | Rabbit |
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| Form & Buffer | Supplied as liquid, in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 0.2-1 ug/ml |
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Storage & Safety
| Storage | Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | CASP8AP2 is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. |
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