PSME2 antibody (70R-9402)
Affinity purified rabbit polyclonal PSME2 antibody
Overview
Overview
| Synonyms | Polyclonal PSME2 antibody, Anti-PSME2 antibody, PSME 2 antibody, PA28B antibody, PSME-2 antibody, PSME-2, PSME2, PSME 2, PA28beta antibody, macropain activator subunit 2, proteasome, prosome, REGbeta antibody, PA28 beta antibody |
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| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | PSME2 antibody was raised in rabbit using the middle region of PSME2 as the immunogen |
| Assay Information | PSME2 Blocking Peptide, catalog no. 33R-8551, is also available for use as a blocking control in assays to test for specificity of this PSME2 antibody |
Images
Western Blot analysis using PSME2 antibody (70R-9402)
PSME2 antibody (70R-9402) used at 0.2-1 ug/ml to detect target protein.
Specifications
| Host | Rabbit |
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| Form & Buffer | Supplied as liquid, in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 0.2-1 ug/ml |
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Storage & Safety
| Storage | Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13. |
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