MAPK1 antibody (70R-9624)
Affinity purified rabbit polyclonal MAPK1 antibody
Overview
Overview
| Synonyms | Polyclonal MAPK1 antibody, Anti-MAPK1 antibody, MAPK 1 antibody, mitogen-activated protein kinase 1 antibody, p38 antibody, PRKM2 antibody, P42MAPK antibody, PRKM1 antibody, p41 antibody, p40 antibody, MAPK2 antibody, MAPK1, ERK antibody, ERK2 antibody, MAPK-1, MAPK-1 antibody, MAPK 1, ERT1 antibody, p41mapk antibody |
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| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | MAPK1 antibody was raised in rabbit using the middle region of MAPK1 as the immunogen |
| Assay Information | MAPK1 Blocking Peptide, catalog no. 33R-7852, is also available for use as a blocking control in assays to test for specificity of this MAPK1 antibody |
Images
Specifications
| Host | Rabbit |
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| Form & Buffer | Supplied as liquid, in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | WB: 0.2-1 ug/ml |
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Storage & Safety
| Storage | Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
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