MRPL45 antibody (70R-10085)
Affinity purified rabbit polyclonal MRPL45 antibody
Overview
Overview
| Synonyms | Polyclonal MRPL45 antibody, Anti-MRPL45 antibody, MRPL45, MRPL 45 antibody, MRPL-45 antibody, MRPL-45, MRPL 45, MGC11321 antibody, mitochondrial ribosomal protein L45 antibody |
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| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | MRPL45 antibody was raised in rabbit using the C terminal of MRPL45 as the immunogen |
| Assay Information | MRPL45 Blocking Peptide, catalog no. 33R-7901, is also available for use as a blocking control in assays to test for specificity of this MRPL45 antibody |
Images
Western Blot analysis using MRPL45 antibody (70R-10085)
Western Blot showing MRPL45 antibody used at a concentration of 1.0 ug/ml against 293T Cell Lysate
Specifications
| Host | Rabbit |
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| Form & Buffer | Supplied as liquid, in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by the end user |
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Storage & Safety
| Storage | Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q. |
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