Cathepsin D antibody (10-2270)
Recombinant Fab monoclonal Cathepsin D antibody
Overview
Overview
| Synonyms | Monoclonal Cathepsin D antibody, Anti-Cathepsin D antibody, CATD antibody, Cathepsin D antibody, Cathepsin D heavy chain antibody, Cathepsin D light chain antibody, ceroid-lipofuscinosis neuronal 10 antibody, CLN10 antibody, CPSD antibody, CTSD antibody, lysosomal aspartyl peptidase antibody, lysosomal aspartyl protease antibody, MGC2311 antibody |
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| Specificity | Human |
| Protein Type | Recombinant |
| Applications | ELISA |
| Assay Information | Cathepsin D antibody pair: 10-2270 can be used as the capture antibody with 10-2271 as the detection antibody for detection of human Cathepsin D in ELISA |
Specifications
| Host | Mouse |
|---|---|
| Clone | M72053 |
| Isotype | IgG1 kappa - Fab fragment |
| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Method of Purification | Cathepsin D antibodies screened using Phage Display system. Expressed in and purified from E. coli. |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied as liquid in 50 mM Potassium Phosphate, 10 mM Boric Acid, 150 mM NaCl, pH 7 |
| Concentration | > 1 mg/ml |
Storage & Safety
| Storage | Store at -20 deg C in small aliquots. Avoid repeated freeze thawing. |
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General Information
| Biological Significance | Cathepsin D is an acid protease active in intracellular protein breakdown. Cathepsin D antibody was produced as a recombinant Fab monoclonal antibody in a Phage Display system. This anti-Cathepsin D antibody is used for detection of human Cathepsin D in ELISA. The concentration of the antibody ranges from 1 mg/ml to 25 mg/ml depending on the lot. Recombinant Fab monoclonal antibodies have a number of advantages over standard antibodies including; improved scale up for batch consistency, more efficient binding so less antibody required, more accurate binding meaning fewer conjugation issues, less non specific due to removal of the Fc region, more flexibility for purification and labeling through a C-terminal His tag. |
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