Cathepsin D protein (30-AC22)
Purified native Human Cathepsin D protein
Overview
Overview
| Species | Human |
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| Protein Type | Native |
| Applications | User optimized |
Specifications
| Source | Human plasma |
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| Grade & Purity | > 98% pure |
| Molecular Weight | 42 kDa |
| Form & Buffer | Lyophilized from 2mM Na3PO4, pH 6.5. Reconstitute with laboratory grade water. |
Usage & Assay Information
| Bioactivity | 300 units/mg -One unit of activity is defined as the amount of enzyme which digests hemoglobin-releasing peptides which are soluble in 10% TCA. The reaction is measured by an increase of an A280 of 1.0 per 60 minutes at 37o C. Substrate: acid denatured he |
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Storage & Safety
| Storage | Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Cathepsin D is a protein that in humans is encoded by the CTSD gene. This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. |
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