Cathepsin H protein (30-AC73)
Purified native Human Cathepsin H protein
Overview
Overview
| Species | Human |
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| Protein Type | Native |
| Applications | User optimized |
Specifications
| Source | Human liver |
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| Grade & Purity | > 80% pure |
| Molecular Weight | 28 kDa |
| Form & Buffer | Frozen in 20mM CH3COONa, pH 4.5, with 1 mM EDTA and 100mM NaCl. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Usage & Assay Information
| Bioactivity | >1 units/mg - One unit of activity is defined as the amount of enzyme which hydrolyzes one uMole of L-arginine-beta-naphtylamide per minute at 40o C in 75 mM potassium phosphate bu er, pH 6.8 with 1 mM EDTA and 3 mM cysteine. |
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Storage & Safety
| Storage | Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests. |
General Information
| Biological Significance | Cathepsin H is a protein that in humans is encoded by the CTSH gene. The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. |
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