CBR1 antibody (10R-11441)
Mouse Monoclonal CBR1 antibody
Overview
Overview
| Synonyms | Monoclonal CBR1 antibody, Anti-CBR1 antibody, Carbonyl reductase 1 antibody, Carbonyl reductase 1 antibody, CBR antibody, hCBR1 antibody, SDR21C1 antibody, CBR1 antibody, Carbonyl reductase 1 15 hydroxyprostaglandin dehydrogenase [NADP+] antibody, Carbonyl reductase [NADPH] 1CBR 1 antibody, CRN antibody, NADPH dependent carbonyl reductase 1 antibody, Prostaglandin 9 ketoreductase antibody, Prostaglandin E(2) 9 reductase |
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| Applications | ELISA, FC, ICC, WB |
| Immunogen | CBR1 antibody was raised in Mouse using recombinant human CBR1 (1-277aa), purified from E. coli, as the immunogen |
Specifications
| Host | Mouse |
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| Clone | AT2D6 |
| Isotype | IgG2a kappa |
| Method of Purification | CBR1 antibody was purified by protein A affinity chromatography |
| Form & Buffer | Supplied in liquid form in Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage or -20 deg C for long term storage |
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General Information
| Biological Significance | Carbonyl reductase 1 (CBR1) is a NADPH-dependent, monomeric, and cytosolic enzyme belonging to a family of short-chain dehydrogenases/reductases. This protein consists of 277 amino acid residues and is widely distributed in human tissues such as liver, epidermis, stomach, small intestine, kidney, neuronal cells, and smooth muscle fiber. CBR1 metabolizes many toxic environmental quinones and pharmacological relevant substrates such as the anticancer drug, doxorubicin. The best substrates of CBR1 are quinones, including ubiquinone-1 and tocophrolquinone (vitamin E). |
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