CCL14 protein (His tag) (80R-1688)
Purified recombinant Human CCL14 protein
|Synonyms||HCC-3 protein, HCC-1 protein, CCL-14 protein, Chemokine (C-C motif) ligand 14, NCC2 protein, CCL 14 protein, FLJ16015 protein, SCYA14 protein, CC-1 protein, SY14 protein, C-C motif chemokine 14 protein, MCIF protein, CC-3 protein, NCC-2 protein, CCL14, CKb1 protein, CCL 14, SCYL2 protein, CCL-14|
Coomassie Blue stained SDS-PAGE of CCL14 protein (His tag) (80R-1688)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||20-93 amino acids: MGSSHHHHHH SSGLVPRGSH MTKTESSSRG PYHPSECCFT YTTYKIPRQR IMDYYETNSQ CSKPGIVFIT KRGHSVCTNP SDKWVQDYIK DMKEN|
|Grade & Purity||> 95% pure|
|Molecular Weight||10.9 kDa (95aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in PBS, pH 7.4, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CCL14, also known as Chemokine (C-C motif) ligand 14, is member of a superfamily of inducible, secreted, proinflammatory cytokines. It has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It also enhances the proliferation of CD34 myeloid progenitor cells. The processed form of CCL14, designated HCC-1(9-74), is a chemotactic factor that attracts monocytes, eosinophils and T cells and is a ligand for CCR1, CCR3 and CCR5. Recombinant human CCL14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.|
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