CCL17 protein (His tag) (80R-1184)
Purified recombinant Human CCL17 protein
|Synonyms||T Cell Directed CC Chemokine protein, Chemokine (C-C motif) ligand 17 A152E53 protein, SCYA17 protein, Chemokine CC Motif Ligand 17 protein, Small Inducible Cytokine A17 Precursor protein, CC Chemokine TARC protein, CCL 17 protein, Thymus and activation regulated chemokine protein, MGC138273 protein, , Small Inducible Cytokine Subfamily A (Cys Cys) Member 17 protein, CCL 17, MGC138271 protein, Small Inducible Cytokine A17 protein, ABCD2 protein, CCL-17 protein, A-152E5.3 protein, CCL17 protein, Small Inducible Cytokine Subfamily A (Cys Cys) protein, CCL17, CCL-17, TARC protein, ABCD-2 protein|
Coomassie Blue stained SDS-PAGE of CCL17 protein (His tag) (80R-1184)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||24-94 amino acids: MGSSHHHHHH SSGLVPRGSH MARGTNVGRE CCLEYFKGAI PLRKLKTWYQ TSEDCSRDAI VFVTVQGRAI CSDPNNKRVK NAVKYLQSLE RS|
|Grade & Purity||> 95% pure|
|Molecular Weight||10.3 kDa (92aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in PBS, pH 7.4, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||CCL17 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). This protein is involved in immunoregulatory and inflammatory processes. It is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL17 was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.|
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