CCL2/MCP1 protein (His tag) (80R-1110)

Purified recombinant Human CCL2/MCP1 protein

Synonyms , SCYA2 protein, CCL2/MCP1, GDCF-2 protein, HC11 protein, CCL/MCP1-2, MCP-1 protein, CCL2 protein, small inducible cytokine A2 (monocyte chemotactic protein 1 homologous to mouse Sig-je) protein, CCL/MCP1 2, Chemokine (C-C motif) ligand 2 protein, MGC9434 protein, MCAF protein, CCL/MCP1-2 protein, MCP1 protein, SMC-CF protein, CCL/MCP1 2 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Specifications

Residues 24-99 amino acids: MGSSHHHHHH SSGLVPRGSH MQPDAINAPV TCCYNFTNRK ISVQRLASYR RITSSKCPKE AVIFKTIVAK EICADPKQKW VQDSMDHLDK QTQTPKT
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 10.9 kDa (97 aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, and 20% glycerol.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels < 1.0 EU per ug of protein (determined by LAL method)

General Information

Biological Significance Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Recombinant human CCL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Availability: In stock

Price: €169.35
Size: 100 ug
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