CCL20 protein (His tag) (80R-1675)
Purified recombinant Human CCL20 protein
|Synonyms||CCL 20, CCL-20, MIP3A protein, CCL20, CCL-20 protein, CCL 20 protein, MIP-3a protein, LARC protein, CKb4 protein, ST38, C-C motif chemokine 20 protein, SCYA20 protein|
Coomassie Blue stained SDS-PAGE of CCL20 protein (His tag) (80R-1675)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||27-96 amino acids: MGSSHHHHHH SSGLVPRGSH MASNFDCCLG YTDRILHPKF IVGFTRQLAN EGCDINAIIF HTKKKLSVCA NPKQTWVKYI VRLLSKKVKN M|
|Grade & Purity||> 85% pure|
|Molecular Weight||10.3 kDa (91aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in PBS, pH 7.4, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CCL20, also known as Macrophage Inflammatory Protein-3 (MIP3A), is a small cytokine belonging to the CC chemokine family. CCL20 protein is strongly chemotactic for lymphocytes and weakly attracts neutrophils. It is implicated in the formation and function of mucosal lymphoid tissues via chemoattraction of lymphocytes and dendritic cells towards the epithelial cells surrounding these tissues. Recombinant human CCL20 protein, fused to His-tag at N-terminus, was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.|
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