CCR6 antibody (10R-1071)

Mouse monoclonal CCR6 antibody

Synonyms Monoclonal CCR6 antibody, Anti-CCR6 antibody, GPR29 antibody, BN-1 antibody, CCR 6, CCR -6, CD196 antibody, DRY-6 antibody, CCR -6 antibody, DCR2 antibody, chemokine (C-C motif) receptor 6 antibody, CCR6, CKR-L3 antibody, CMKBR6 antibody, GPR-CY4 antibody, CCR 6 antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen CCR6 antibody was raised in mouse using recombinant human CCR6 (1-46aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone 4C6
Isotype IgG1 kappa
Source Anti-human CCR6 antibody, clone 4C6, is derived from hybridization of mouse F0myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CCR6 protein.
Method of Purification CCR6 antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. CCR6 has been reported to be expressed in intestine, colon, liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It has also been reported to be expressed in lymphocytes, T cells, and B cells.

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Availability: In stock

Price: €249.33
Size: 100 ul
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