CD105 protein (Mouse) (30R-ACD105)
Purified recombinant Mouse CD105 protein
Overview
Overview
| Synonyms | Mouse Endoglin protein, CD-105, Murine Endoglin protein, CD 105 protein, CD 105, CD-105 protein, Murine CD105 protein, CD105 |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Expression System | Sf-9 insect cells |
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| Grade & Purity | > 95% pure |
| Molecular Weight | ~85 kDa |
| Form & Buffer | Supplied as a lyophilized powder. Reconsitute by adding a carrier protein (e.g. 0.1% HSA or BSA) which allows for long term storage. |
Storage & Safety
| Storage | Store at -70 deg C until reconstitution. Following reconstitution product should be aliquoted and frozen at -20 deg C. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | <0.1 ng per ug of sCD105 |
General Information
| Biological Significance | Endoglin (CD105) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Endoglin has been found to be part of the TGF-beta1 receptor complex. It thus may be involved in the binding of TGF-beta1, TGF-beta3, activin-A, BMP-2, and BMP-7. |
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