CD11a antibody (biotin) (61R-CD11aaMSBT)

Rat monoclonal CD11a antibody (biotin)

Synonyms Monoclonal CD11a antibody, Anti-CD11a antibody, CD11a, CD-11a antibody, CD 11a antibody, LFA1a antibody, CD-11a, CD 11a
Specificity Murine CD11a
Cross Reactivity To be determined by end-user
Applications FC, IHC, IP, WB
Immunogen CD11a antibody (biotin) was raised in rat using murine CD11a (LFA-1a) as the immunogen.

Specifications

Host Rat
Clone I21/7
Isotype IgG2a
Tag/Conjugate Biotin
Form & Buffer Supplied as a liquid in PBS, with NaN3 added as preservative.
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a human gene which functions in the immune system. It is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab. ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling.

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Availability: In stock

Price: €334.00
Size: 500 ug
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