CD11b antibody (10R-CD11bgMS )
Rat monoclonal CD11b antibody
Overview
Overview
| Synonyms | Monoclonal CD11b antibody, Anti-CD11b antibody, CD-11b antibody, CD11B Ma-1c antibody, Ma-1c antibody, Rat Macrophages+Microglial cells antibody, MAC1 antibody, CD11b, CD 11b antibody, Mac1a antibody, CD 11b, MA-1c antibody, CD-11b, Integrin alpha M antibody |
|---|---|
| Specificity | Murine CD11b |
| Cross Reactivity | To be determined by end-user |
| Applications | FC, IP |
| Immunogen | CD11b antibody was raised in rat using peritoneal macrophages from C57 B1/6 x DBA/2 F1 hybrid mice as the immunogen. |
Images
Flow Cytometric assay using CD11b antibody (10R-CD11bgMS)
Flow Cytometric assay showing isotype control vs MAC1+ cells using CD11b antibody (10R-CD11bgMS)
Specifications
| Host | Rat |
|---|---|
| Clone | 3A33 |
| Isotype | IgG2a |
| Form & Buffer | Supplied as a liquid in 100mM BBS, pH 8.2. |
| Concentration | 0.5 mg/ml |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by end user |
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Storage & Safety
| Storage | Store at 4 deg C. |
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General Information
| Biological Significance | Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 ( alphaMBeta2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A, and cluster of differentiation molecule 11B (CD11B). The second chain of alphaMBeta2 is the common integrin Beta2 subunit known as CD18, and integrin alphaMBeta2 thus belongs to the Beta2 subfamily (or leukocyte) integrins. |
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