Monoclonal CD11b antibody, Anti-CD11b antibody, CD11b, CD 11b antibody, MA-1c antibody, Rat Macrophages+Microglial cells antibody, Mac1a antibody, CD-11b, CD11B Ma-1c antibody, CD 11b, Ma-1c antibody, MAC1 antibody, CD-11b antibody
Specificity
Murine CD11b
Cross Reactivity
To be determined by end-user
Applications
FC, IHC, IP
Immunogen
CD11b antibody (Azide Free) was raised in rat using C57BL/10 murine splenic T cells and concanavalin A-activated C57BL/10 splenocytes as the immunogen.
Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles
General Information
Biological Significance
Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 ( alphaMBeta2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A, and cluster of differentiation molecule 11B (CD11B). The second chain of alphaMBeta2 is the common integrin Beta2 subunit known as CD18, and integrin alphaMBeta2 thus belongs to the Beta2 subfamily (or leukocyte) integrins.