CD11b antibody (FITC) (61R-1051)
Rat monoclonal CD11b antibody (FITC)
Overview
Overview
| Synonyms | Monoclonal CD11b antibody, Anti-CD11b antibody, CD-11b antibody, CR3 antibody, CD11b, CD-11b, Ma-1c antibody, CD 11b, CD 11b antibody, integrin alpha M antibody, ITGAM antibody |
|---|---|
| Specificity | Mouse |
| Applications | FC |
| Assay Information | The pre-titrated test size contains 0.2% BSA. |
Images
Flow Cytometric analysis using CD11b antibody (FITC) (61R-1051)
Staining of mouse bone marrow cells with 0.25 ug of Rat IgG2b K Isotype Control (FITC) or 0.25 ug of CD11b antibody (FITC). Cells in the lymphoid (top) or myeloid (bottom) gate were used for analysis.
Specifications
| Host | Rat |
|---|---|
| Clone | M1/70 |
| Isotype | IgG2b kappa |
| Tag/Conjugate | FITC |
| Form & Buffer | Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
| Concentration | 20 ul (0.25 ug)/test |
Usage & Assay Information
| Usage Recommendations | FC: 20 ul (0.25 ug)/test |
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Storage & Safety
| Storage | Store at 2-8 deg C. Do not freeze. Protect from light. |
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General Information
| Biological Significance | The M1/70 monoclonal antibody reacts with mouse CD11b, the 165-170 kDa integrin alphaM. CD11b non-covalently associates with CD18 to form alphaMbeta2 integrin and binds to CD54, C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions. |
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