Monoclonal CD11b antibody, Anti-CD11b antibody, CD 11b, CD11b, MA-1c antibody, CD11B Ma-1c antibody, CD-11b, Ma-1c antibody, CD-11b antibody, Rat Macrophages+Microglial cells antibody, MAC1 antibody, CD 11b antibody, Mac1a antibody
Specificity
Murine CD11b
Cross Reactivity
To be determined by end-user
Applications
FC, IHC
Immunogen
CD11b antibody (Spectral Red) was raised in rat using C57BL/10 murine splenic T-cells and concanavalin A-activted C57BL/10 splenocytes as the immunogen.
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
General Information
Biological Significance
Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 ( alphaMBeta2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A, and cluster of differentiation molecule 11B (CD11B). The second chain of alphaMBeta2 is the common integrin Beta2 subunit known as CD18, and integrin alphaMBeta2 thus belongs to the Beta2 subfamily (or leukocyte) integrins.