CD133 antibody (10R-8653)
Rat monoclonal CD133 antibody
Overview
Overview
| Synonyms | Monoclonal CD133 antibody, Anti-CD133 antibody, PROM1 antibody, AC133 antibody, CD133 antibody, CORD12 antibody, MCDR2 antibody, PROML1 antibody, RP41 antibody, STGD4 antibody, Prominin 1 antibody, AC133 antibody, CD 133 antibody, CD-133 antibody, CD133 |
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| Cross Reactivity | Mouse |
| Applications | FC, IHC, IP, WB |
| Immunogen | CD133 antibody was raised in Rat using mouse Prominin 1 (CD133) as the immunogen |
Specifications
| Host | Rat |
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| Clone | 13A4 |
| Isotype | IgG1 kappa |
| Method of Purification | CD133 antibody was purified using protein A purification |
| Molecular Weight | 115 kDa |
| Form & Buffer | Supplied in liquid form in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative |
| Concentration | 1.0 mg/ml |
Usage & Assay Information
| Usage Recommendations | IHC: 1-15 ug/ml |
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Storage & Safety
| Storage | Stable for 1 year at 2-8 deg C |
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General Information
| Biological Significance | CD133 is expressed in hematopoietic stem cells, endothelial progenitor cells, glioblastoma, neuronal and glial stem cells, various pediatric brain tumors, as well as adult kidney, mammary glands, trachea, salivary glands, placenta, digestive tract, testes, and some other cell types. Recent studies in brain tumors have identified a CD133+ cell population thought to be a cancer stem cell population, which is rare, undergoes self-renewal and differentiation, and can propagate tumors when injected into immune-compromised mice. However, subsequent studies have indicated the difficulty in isolating pure CSC populations. |
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