CD14 protein (80R-4320)

Purified Recombinant CD14 protein (His tagged)

Synonyms CD14 antigen
Species Mouse
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis using CD14 protein (His tag) (80R-4320)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 16-366 aa: SPAPPEPCEL DEESCSCNFS DPKPDWSSAF NCLGAADVEL YGGGRSLEYL LKRVDTEADL GQFTDIIKSL SLKRLTVRAA RIPSRILFGA LRVLGISGLQ ELTLENLEVT GTAPPPLLEA TGPDLNILNL RNVSWATRDA WLAELQQWLK PGLKVLSIAQ AHSLNFSCEQ VRVFPALSTL DLSDNPELGE RGLISALCPL KFPTLQVLAL RNAGMETPSG VCSALAAARV QLQGLDLSHN SLRDAAGAPS CDWPSQLNSL NLSFTGLKQV PKGLPAKLSV LDLSYNRLDR NPSPDELPQV GNLSLKGNPF LDSESHSEKF NSGVVTAGAP SSQAVALSGT LALLLGDRLF VHHHHHH
Expression System Insect cells
Grade & Purity > 90% pure
Molecular Weight 38.3 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in PBS buffer (pH 7.4) containing 10% glycerol
Concentration 500 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage, aliquot and store at -20 or -70 deg C. Avoid repeat freeze/thaw cycles
Endotoxin Levels < 1.0 EU per 1 microgram of protein

General Information

Biological Significance Cd14, also known as monocyte differentiation antigen CD14, is a component of the innate immune system. This protein was found expressed in macrophages, neutrophil granulocyte and dendritic cells. It exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol tail (mCD14), the other a soluble form (sCD14). The major function is serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns. Recombinant Mouse Cd14, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

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Images

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SDS-PAGE analysis using CD14 protein (His tag) (80R-4320)



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Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €306.75
Size: 50 ug
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