CD154 antibody (10R-6494)

Mouse monoclonal CD154 antibody

Synonyms Monoclonal CD154 antibody, Anti-CD154 antibody, CD154, CD 154 antibody, TRAP antibody, Tnfsf5 antibody, CD-154 antibody, CD-154, CD40L antibody, CD 154
Specificity Human
Cross Reactivity Cynomolgus Monkey
Applications FC, Functional Assay, IHC
Assay Information A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest.

Specifications

Host Mouse
Clone 24-31
Isotype IgG1 kappa
Method of Purification CD154 antibody was purified by affinity chromatography.
Form & Buffer Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
Concentration 500 ug/ml

Usage & Assay Information

Usage Recommendations FC: = 0.125 ug/test

Storage & Safety

Storage Store at 2-8 deg C. Do not freeze. Protect from light.

General Information

Biological Significance The 24-31 monoclonal antibody reacts with human CD154, a 39 kDa transmembrane glycoprotein also known as gp39 and CD40 ligand. CD154 is a member of the TNF superfamily and is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells including B cells, monocytes/macrophages and dendritic cells, CD154 serves a crucial function in T-APC cognate interaction. CD154 interaction with CD40 transduces signals for T-dependent B-cell activation and induces B cell cycle entry. 24-31 cross-reacts with the cynomolgus monkey CD154.

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Price From: Price: €140.70

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Price From: Price: €140.70
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