CD18 antibody (10R-CD18eMS)

Rat monoclonal CD18 antibody

Synonyms Monoclonal CD18 antibody, Anti-CD18 antibody, CD 18, beta 2 Integrin antibody, b2 Integrin antibody, CD-18 antibody, CD 18 antibody, CD18, CD-18
Specificity Murine CD18
Cross Reactivity To be determined by end-user
Applications FC, IHC, IP, WB
Immunogen CD18 antibody was raised in rat using cell membrane lysates derived from murine T cell lymphoma BW5147 as the immunogen.

Specifications

Host Rat
Clone C71/16
Isotype IgG2a
Form & Buffer Supplied as a liquid in 100mM BBS, pH 8.2.
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 2-8 deg C

General Information

Biological Significance Integrin beta-2 (CD18) is a protein that in humans is encoded by the ITGB2 gene. The ITGB2 protein product is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. In humans lack of CD18 causes Leukocyte Adhesion Deficiency, a disease defined by a lack of leukocyte extravasation from blood into tissues.

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Availability: In stock

Price: €296.37
Size: 500 ug
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