CD19 antibody (10R-CD19aMS)

Rat monoclonal CD19 antibody

Synonyms Monoclonal CD19 antibody, Anti-CD19 antibody, CD 19, CD-19 antibody, CD19, CD-19, CD 19 antibody
Specificity Murine CD19
Cross Reactivity To be determined by end-user
Applications FC, IP
Immunogen CD19 antibody was raised in rat using Mouse CD19-expressing K562 human erythroleukemia cells as the immunogen.

Specifications

Host Rat
Clone 6D5
Isotype IgG2a
Form & Buffer Supplied as a liquid in 100mM BBS, pH 8.2.
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.

General Information

Biological Significance B-lymphocyte antigen CD19 also known as CD19 (Cluster of Differentiation 19), is a protein that in humans is encoded by the CD19 gene. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase.

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Availability: In stock

Price: €334.00
Size: 500 ug
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