CD1c antibody (FITC) (61R-1029)
Mouse monoclonal CD1c antibody (FITC)
Overview
Overview
| Synonyms | Monoclonal CD1c antibody, Anti-CD1c antibody, CD1c, BDCA-1 antibody, CD-1c antibody, CD 1c antibody, CD 1c, CD-1c |
|---|---|
| Specificity | Human |
| Applications | FC, IHC, IP |
| Assay Information | A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. |
Images
Flow Cytometric analysis using CD1c antibody (FITC) (61R-1029)
Staining of normal human peripheral blood cells with CD19 antibody and Mouse IgG1 K Isotype Control (FITC) (left) or Anti-Human CD1c (right). Total viable cells were used for this analysis.
Specifications
| Host | Mouse |
|---|---|
| Clone | L161 |
| Isotype | IgG1 |
| Tag/Conjugate | FITC |
| Form & Buffer | Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
| Concentration | 5 ul/mg |
Usage & Assay Information
| Usage Recommendations | FC: 5 ul (0.06 ug)/test |
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Storage & Safety
| Storage | Store at 2-8 deg C. Do not freeze. Protect from light. |
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General Information
| Biological Significance | This L161 monoclonal antibody detects CD1c, a glycoprotein that is noncovalently linked to beta-2 microglobulin on thymocytes and antigen presenting cells such as dendritic and Langerhans cells. This molecule is also expressed on some circulating and marginal zone B cells, as well as in lymph nodes and germinal centers. CD1c is involved in the presentation of lipid antigens such as microbial fatty acids to effector T cells during the adaptive immune response. Finally, alternative splicing gives rise to three different isoforms of CD1c. |
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