CD23 antibody (Azide Free) (10R-CD23cMSP)
Rat monoclonal CD23 antibody (Azide Free)
Overview
Overview
| Synonyms | Monoclonal CD23 antibody, Anti-CD23 antibody, CD 23, CD 23 antibody, Fc-epsilon-RII antibody, BLAST-2 antibody, CD23, Lymphocyte IgE receptor antibody, CD-23, CD-23 antibody, FCeRII antibody, CD23 antigen antibody |
|---|---|
| Specificity | Murine |
| Cross Reactivity | To be determined by end-user |
| Applications | FC, IP |
| Immunogen | CD23 antibody (Azide free) was raised in rat using CD23 low affinity IgE Fc receptor as the immunogen. |
Specifications
| Host | Rat |
|---|---|
| Clone | 2G8 |
| Isotype | IgG2a |
| Form & Buffer | Supplied as a liquid in PBS. |
| Concentration | 0.5 mg/ml |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by end user |
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Storage & Safety
| Storage | Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles |
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General Information
| Biological Significance | CD23, also known as Fc epsilon RII, or FceRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. |
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