CD25 antibody (10R-CD25dMS)

Rat monoclonal CD25 antibody

Synonyms Monoclonal CD25 antibody, Anti-CD25 antibody, CD-25 antibody, CD-25, IL2Ra antibody, CD 25, CD25, CD25 IL2-R alpha TAC antibodyIL2-R alpha TAC antibody, CD 25 antibody
Specificity Murine CD25
Cross Reactivity To be determined by end-user
Applications FC, IP
Immunogen CD25 antibody was raised in rat using IL-2-dependent BALB/c murine helper T-cell as the immunogen.

Specifications

Host Rat
Clone 7D4
Isotype IgM
Form & Buffer Supplied as a liquid in 100mM BBS, pH 8.2.
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.

General Information

Biological Significance CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression.

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Availability: In stock

Price: €296.37
Size: 500 ug
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