CD274 protein (His tag) (80R-2388)
Purified recombinant Mouse CD274 protein (His tag)
Overview
Overview
| Synonyms | CD-274 protein, CD 274 protein, B7h1 protein, CD274, Pdcd1l1 protein, CD 274, Pdl1 protein, A530045L16Rik protein, CD274 antigen protein, CD-274, Pdcd1lg1 protein |
|---|---|
| Species | Mouse |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
Coomassie Blue stained SDS-PAGE of CD274 protein (His tag) (80R-2388)
Figure annotation denotes ug of protein loaded and % gel used.
Specifications
| Residues | MGSSHHHHHH SSGLVPRGSH MGSHMFTITA PKDLYVVEYG SNVTMECRFP VERELDLLAL VVYWEKEDEQ VIQFVAGEED LKPQHSNFRG RASLPKDQLL KGNAALQITD VKLQDAGVYC CIISYGGADY KRITLKVNAP YRKINQRISV DPATSEHELI CQAEGYPEAE VIWTNSDHQP VSGKRSVTTS RTEGMLLNVT SSLRVNATAN DVFYCTFWRS QPGQNHTAEL IIPELPATHP PQNRTH |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 85% pure |
| Molecular Weight | 27.6 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in liquid form in 20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.15M NaCl |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 or -70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | CD274, also known as programmed cell death 1 ligand 1(PDCD1L1), is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. This protein interacts with PDCD1 inhibits T-cell proliferation and cytokine production. Recombinant mouse CD274 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
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