CD3 antibody (10R-6329)
Armenian Hamster monoclonal CD3 antibody
Overview
Overview
| Synonyms | Monoclonal CD3 antibody, Anti-CD3 antibody, CD-3, CD-3 antibody, CD 3 antibody, CD3 epsilon antibody, CD 3, CD3 |
|---|---|
| Specificity | Mouse |
| Applications | ELISA |
Images
Flow Cytometric analysis using CD3 antibody (10R-6329)
Staining of C57Bl/6 splenocytes with Armenian Hamster IgG Isotype Control (open histogram) or CD3e antibody (filled histogram) followed by Anti-Armenian Hamster IgG (FITC). Total viable cells were used for analysis.
Specifications
| Host | Hamster |
|---|---|
| Clone | 145-2C11 |
| Isotype | IgG |
| Method of Purification | CD3 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
| Concentration | 500 ug/ml |
Storage & Safety
| Storage | Store at 2-8 deg C. Do not freeze. Protect from light. |
|---|
General Information
| Biological Significance | The 145-2C11 monoclonal antibody reacts with mouse CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells. |
|---|
Reviews
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product