CD3 antibody (allophycocyanin) (61R-1698)
Armenian Hamster monoclonal CD3 antibody (allophycocyanin)
Overview
Overview
| Synonyms | Monoclonal CD3 antibody, Anti-CD3 antibody, CD-3 antibody, CD-3, CD3 antibody (APC), CD 3, CD 3 antibody, CD3 epsilon antibody, CD3 |
|---|---|
| Specificity | Mouse |
| Applications | WB |
| Assay Information | The T3.7C3 antibody has been tested by immunoblotting of mTLR3 transfected cell lysate and can be used at 1-3ug/ml. |
Images
Flow Cytometric analysis using CD3 antibody (allophycocyanin) (61R-1698)
Staining of C57Bl/6 splenocytes with CD45R antibody (FITC) and 0.125 ug of Armenian Hamster IgG Isotype Control (left) or 0.125 ug of CD3e antibody (right). Total viable cells were used for analysis.
Specifications
| Host | Hamster |
|---|---|
| Clone | 145-2C11 |
| Isotype | IgG |
| Tag/Conjugate | Allophycocyanin |
| Form & Buffer | Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
| Concentration | 500 ug/ml |
Storage & Safety
| Storage | Store at 2-8 deg C. Do not freeze. Protect from light. |
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General Information
| Biological Significance | The 145-2C11 monoclonal antibody reacts with mouse CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells. |
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