CD31 antibody (10R-CD31cHU)
Mouse monoclonal CD31 antibody
Overview
Overview
| Synonyms | Monoclonal CD31 antibody, Anti-CD31 antibody, Platelet Endothelial Cell Adhesion Molecule antibody, EndoCAM antibody, GPIIA antibody, PECAM1 antibody, PECAM-1 antibody, CD 31 antibody, CD-31, CD-31 antibody, CD 31, CD31 |
|---|---|
| Specificity | Human |
| Cross Reactivity | To be determined by end-user |
| Applications | IHC-P |
| Immunogen | CD31 antibody was raised in mouse using prokaryortic recombinant fusion of protein corresponding to a portion of the extracelluar domain downstream of the signal sequence of the CD31 molecule as the immunogen. |
Images
Immunohistochemical staining using CD31 antibody (10R-CD31cHU)
Immunohistochemical staining for CD31 antigen (PECAM1) using 10R-CD31cHU. Note intense membrane staining of endothelial cells
Specifications
| Host | Mouse |
|---|---|
| Clone | 1A10 |
| Isotype | IgG1 |
| Form & Buffer | Lyophilized tissue culture supernatant containing 15mM NaN3. Reconstitute with 1 ml of sterile distilled water. |
Usage & Assay Information
| Usage Recommendations | IHC-P:1:50-1:100 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. |
General Information
| Biological Significance | The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. |
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