CD3G protein (His tag) (80R-2704)
Purified recombinant CD3G protein (His tag)
|Synonyms||CD3g molecule protein, gamma (CD3-TCR complex) protein, CD3-GAMMA protein, T3G protein, CD3G, CD 3G, CD-3G, CD 3G protein, CD-3G protein|
SDS-PAGE analysis of CD3G protein (His tag) (80R-2704)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||23-116 aa: MGSSHHHHHH SSGLVPRGSH MGSQSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATIS|
|Grade & Purity||> 90% pure|
|Molecular Weight||13.1 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol|
Storage & Safety
|Storage||Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles|
|Biological Significance||The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. Recombinant human CD3G protein, fused to His-tag at N-terminus, was expressed in E.coli.|
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