CD4 antibody (10-Z04A)
Mouse monoclonal CD4 antibody
Overview
Overview
| Synonyms | Monoclonal CD4 antibody, Anti-CD4 antibody, p55 antibody, CD4_HUMAN antibody, Leu3 antibody, T Cell Antigen T4 antibody, T Cell Surface Glycoprotein CD4 antibody, included antibody, W3/25 antibody, Ly-4 antibody, T cell surface antigen T4/Leu3 antibody, L3T4 antibody, W3/25 antigen antibody, MGC165891 antibody, CD-4, T cell surface antigen T4/Leu 3 antibody, T-cell surface antigen T4/Leu-3 antibody, Lymphocyte antigen CD4 antibody, included antibody, L3T4 antibody, CD4+ Lymphocyte deficiency, T-cell surface glycoprotein CD4 antibody, T cell differentiation antigen L3T4 antibody, T cell antigen T4/LEU3 antibody, CD4 antigen (p55) antibody, T cell OKT4 deficiency, CD 4, CD4, , CD-4 antibody, CD4mut antibody, CD 4 antibody |
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| Specificity | Human |
| Applications | Functional Assay |
| Immunogen | CD4 antibody was raised in mouse using hybridoma of X63.653 myeloma with spleen cells of Balb/c mice immunized with normal human blood lymphocytes. |
| Assay Information | Can be used to enumerate T helper/inducer subset in peripheral blood and tissue. |
Specifications
| Host | Mouse |
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| Clone | M504505 |
| Isotype | IgG1 |
| Method of Purification | CD4 antibody was purified by chromatography on protein A Sepharose. |
| Form & Buffer | Purified from murine ascites by column chromatography and supplied in PBS, pH 7.5, with 0.1% NaN3. |
| Concentration | Batch dependent - please inquire should you have specific requirements |
Usage & Assay Information
| Usage Recommendations | Use at 1:4000 as a working dilution. |
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Storage & Safety
| Storage | Store at 4 deg C. |
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| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
General Information
| Biological Significance | CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4 monoclonal antibody that reacted with it) before being named CD4 in 1984. In humans, the CD4 protein is encoded by the CD4 gene. |
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