CD4 antibody (10R-6332)

Rat monoclonal CD4 antibody

Synonyms Monoclonal CD4 antibody, Anti-CD4 antibody, CD4, CD-4, Ly-4 antibody, L3T4 antibody, CD-4 antibody, CD 4, CD 4 antibody
Specificity Mouse
Applications ELISA

Images

Flow Cytometric analysis using CD4 antibody (10R-6332)

Staining of C57Bl/6 splenocytes with 0.06 ug of Rat IgG2b Isotype Control (open histogram) or 0.06 ug of CD4 antibody (filled histogram) followed by Anti-Rat IgG (FITC). Total viable cells were used for analysis.

Specifications

Host Rat
Clone GK1.5
Isotype IgG2b kappa
Method of Purification CD4 antibody was purified by affinity chromatography.
Form & Buffer Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
Concentration 500 ug/ml

Storage & Safety

Storage Store at 2-8 deg C. Do not freeze. Protect from light.

General Information

Biological Significance The GK1.5 monoclonal antibody reacts with the mouse CD4 molecule, a 55 kDa cell surface receptor expressed by a majority of thymocytes, subpopulation of mature T cells and dendritic cells. CD4 binds to MHC class II on the surface of antigen presenting cells and plays an important role both in T cell development and in optimal functioning of mature T cells. In T cells, CD4 associates with protein tyrosine kinase p56lck through its cytoplasmic tail. Binding of GK1.5 is blocked by RM4-5.

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Images

  • Flow Cytometric analysis using CD4 antibody (10R-6332) | Staining of C57Bl/6 splenocytes with 0.06 ug of Rat IgG2b Isotype Control (open histogram) or 0.06 ug of CD4 antibody (filled histogram) followed by Anti-Rat IgG (FITC). Total viable cells were used for analysis.

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Price From: Price: €69.53

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Price From: Price: €69.53
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