CD4 protein (30-013101)
Purified recombinant Human CD4 protein
Overview
Overview
| Synonyms | CD 4, CD 4 protein, CD-4 protein, gp55 protein, soluble CD4 protein, sCD4 protein, L3 / T4 protein, T cell antigen T4/LEU3 protein, HLA-2 protein, CD-4, CD4, CD4mut protein, Ly-4 protein, T4 protein |
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| Species | Human |
| Protein Type | Recombinant |
| Applications | ELISA, WB |
Specifications
| Expression System | CHO cells |
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| Grade & Purity | > 95% pure |
| Form & Buffer | Supplied lyophlized in 50mM MES, pH 6.0, 350 mM NaCl buffer |
Usage & Assay Information
| Usage Recommendations | ELISA: 1 ug/ml, WB: 1 ug/ml |
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Storage & Safety
| Storage | Store at 2-8 deg C, freeze reconstituted product in working aliquots at -70 deg C |
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General Information
| Biological Significance | CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. (Some cytotoxic T cells have CD4 protein as well.) Normally, about 65% of T cells in the blood are CD4+ (have CD4 protein protruding from their membrane). A mature T cell with either have CD4 or CD8, but not both. During one stage of development T cells develop CD4 and CD8 receptors, but they eventually are differentiated in the thymus and become more specialized. |
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